Microinjected Coxsackie B1 virus does not replicate in HEp-2 cell

Kristin R. Modalsli, Geir Bukholm, Svein-Ole Mikalsen, Miklos Degré

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


Coxsackie B1 virus did not replicate when microinjected into HEp-2 cells. Replication was assayed by production of infectious virus particles, synthesis of viral RNA, and lysis of cells. The same virus preparation initiated replication when it was inoculated into HEp-2 cells similarly to that by microinjected purified coxsackie B1 virus RNA.
Original languageEnglish
Pages (from-to)888-890
Number of pages3
Issue number2
Publication statusPublished - 1991
Externally publishedYes


  • Coxsackie B1 virus
  • viral replication
  • microinjection
  • Cell culture


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