Feasibility and impact of whole-body high-intensity interval training in patients with stable coronary artery disease: a randomised controlled trial

Jacobina Kristiansen, Tórur Sjúrðarson, Erik Lerkevang Grove, Jan Rasmussen, Steen Dalby Kristensen, Anne-Mette Hvas, Magni Mohr

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

Exercise training reduces cardiovascular mortality and improves quality of life in CAD patients. We investigated the feasibility and impact of 12 weeks of low-volume high-intensity interval training (HIIT) in CAD-patients. Patients with stable CAD were randomized 1:1 to supervised HIIT or standard care. HIIT sessions were completed three times weekly for 12 weeks on a rowing ergometer. Before and after the 12-week intervention, patients completed a physiological evaluation of cardiorespiratory performance and quality of life questionnaires. Mixed model analysis was used to evaluate differences between and within groups. A total of 142 patients (67 ± 9 years, nHIIT = 64, nStandard care = 78) completed the trial. Training adherence was 97% (range 86–100%). Six patients dropped out because of non-fatal adverse events. Weekly training duration was 54 min with an average power output of 138 W. HIIT increased peak oxygen uptake by 2.5 mL/kg/min (95% CI 2.1–3.0), whereas no change was observed in standard care (0.2 mL/kg/min, 95% CI − 0.2–0.6, P 
Original languageEnglish
Pages (from-to)17295
Number of pages12
JournalSCIENTIFIC REPORTS
Volume12
Issue number1
DOIs
Publication statusPublished - 14 Oct 2022

Keywords

  • exercise training
  • cardiovascular mortality
  • cardiovascular health
  • Coronary artery disease

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